Blackburn Rovers lifted themselves from the foot of the table after scoring three times, to earn a famous 3-2 victory at Old Trafford at odds of 28-1 at Victor Chander.
Didier Drogba scored his 150th goal for Chelsea from the penalty spot but it was not enough as Chelsea lost 1-3 to Aston Villa at Stamford Bridge. Stephen Ireland hit back for Villa five minutes later before Stiliyan Petrov gave Villa the lead in the 83rd minute and Darren Bent scored Villa's third three minutes later.
Tottenham drew 1-1 against Swansea at the Liberty Stadium to reduce the gap to second-placed United to six points.
Robin Van Persie's second-half strike gave Arsenal a 1-0 win over QPR at the Emirates after the Gunners missed several chances in an entertaining match.
Results from Dec 31st 2011
Arsenal 1-0 QPR
Bolton 1-1 Wolves
Chelsea 1-3 Aston Villa
Man Utd 2-3 Blackburn
Norwich 1-1 Fulham
Stoke 2-2 Wigan
Swansea 1-1 Tottenham
English Premier League - Top 6 Standings